Production of Therapeutic Proteins by Genetic Engineering | Gish, DT. 1998.
Impact 299:i-iv. CELD ID 2889Abstract The March 1998 Impact No. 297 discussed the procedure of cloning by somatic cell transfer. In that procedure, the nucleus from a cell derived from an embryo, a fetus, or tissue of an adult is inserted into an egg from which the nucleus has been removed. After the egg develops to the appropriate stage, the embryo is inserted into the uterus of a properly prepared female and allowed to develop to term. This produces an offspring essentially genetically identical to the animal that provided the nucleus that was inserted into the egg. This article will discuss the transfer of genes from one species to another in order to endow the recipient species with beneficial properties, or to enable the recipient to produce human proteins for injection into human patients who lack a vitally important protein.
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