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The sickle cell trait
McLeod, KC. 1982.  CRSQ 19(1):19-26. CELD ID 2223

Abstract
The sickle cell story is often put forward as a demonstration of evolution. Here recent medical knowledge concerning the trait is reviewed. It is seen that in sickle cell nothing has evolved, improved, or increased in complexity. All that happens is that in this case protection against one disease, malaria, is conferred by another disease, sickle cell.