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Descendents can overcome parental mutations
Coppedge, D. 2005.  CM 10(2):11. CELD ID 20330

Abstract
Bad genes from both parents may not spell doom in all cases, according to a report in Nature . As reported by Purdue University News , if two parents have bad mutations, the child can sometimes reconstruct the correct gene from the grandparents. "Our genetic training tells us that's just not possible," said Bob Pruitt, co-researcher on the team that ran the experiment repeatedly with the lab plant Arabidopsis. "This challenges everything we believe."