Abstract
From its inception in the sixteenth century, natural science has sought to construct a complete mathematical model of physical reality. This goal was based on three assumptions: (1) that mathematics was equal to the task; (2) that humans, insofar as they perceived the world, perceived it as it is; and (3) that the universe would reveal itself to be fundamentally fairly simple. Today we recognize that not only are all three of these assumptions flawed, their flaws are interrelated and, because of that, formulating a complete mathematical model of physical reality may be beyond our ability. In this paper, I discuss this development in light of William Wharton's work and close with a comment on what this might mean for scientists who are also Christians.