Abstract
In this paper, I will consider some underlying principles important for scientific research and some of the presuppositions that undergird our scientific endeavor. In June 1988, I attended an interdisciplinary conference in Tacoma, Washington, entitled "Information Content of DNA," which dealt with many of the topics that I am concerned with in this paper. I will discuss subsequently some of the contributions of these individuals to my current thinking. I will also refer to other prominent scientists whose research and writings have helped to mold my views. One of the latter is Dr. Roger Williams of The University of Texas who made the following comment in a lecture; he thought it may have come originally from one of the Wright brothers: If everyone accepted as true what is generally believed to be true, there would be no room for advances.